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Research Highlights

Research Highlights /

Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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Synthetic protein quality control to enhance full-length translation in bacteria

Synthetic protein quality control to enhance full-length translation in bacteria

Prof. Sang Woo Seo

Coupled transcription and translation processes in bacteria cause indiscriminate translation of intact and truncated messenger RNAs, inevitably generating nonfunctional polypeptides.

Vibrio cholerae FruR facilitates binding of RNA polymerase to the fru promoter in the presence of fructose 1-phosphate

Vibrio cholerae FruR facilitates binding of RNA polymerase to the fru promoter in the presence of fructose 1-phosphate

Prof. Yeong-Jae Seok

In most bacteria, efficient use of carbohydrates is primarily mediated by the phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS), which concomitantly phosphorylates the substrates during import.

Reversible disorder-order transitions in atomic crystal nucleation

Reversible disorder-order transitions in atomic crystal nucleation

Prof. Jungwon Park

Nucleation in atomic crystallization remains poorly understood, despite advances in classical nucleation theory.

Highly luminescent and catalytically active suprastructures of magic-sized semiconductor nanoclusters

Highly luminescent and catalytically active suprastructures of magic-sized semiconductor nanoclusters

Prof. Taeghwan Hyeon

Metal chalcogenide magic-sized nanoclusters have shown intriguing photophysical and chemical properties, yet ambient instability has hampered their extensive applications. Here we explore the periodic assembly of these nanoscale building blocks through organic linkers to overcome such limitations and further boost thei...

FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo

FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo

Prof. Jong-Seo Kim, V Narry Kim

RNA–protein interaction is central to post-transcriptional gene regulation. Identification of RNA-binding proteins relies mainly on UV-induced crosslinking (UVX) followed by the enrichment of RNA–protein conjugates and LC-MS/MS analysis.

PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics

PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics

Identifying and interpreting pleiotropic loci is essential to understanding the shared etiology among diseases and complex traits.

Single EMG Sensor-Driven Robotic Glove Control for Reliable Augmentation of Power Grasping

Single EMG Sensor-Driven Robotic Glove Control for Reliable Augmentation of Power Grasping

Prof. Jooeun Ahn

The practical operation of wearable robots requires intuitive, compact, yet reliable control interfaces.

Emotional well-being and gut microbiome profiles by enterotype

Emotional well-being and gut microbiome profiles by enterotype

Prof. Jongsik Chun & Incheol Choi

With increasing attention being paid to improving emotional well-being, recent evidence points to gut microbiota as a key player in regulating mental and physical health via bidirectional communication between the brain and gut.

Fingerprint ridges allow primates to regulate grip

Fingerprint ridges allow primates to regulate grip

Prof. Gun-Sik Park

Here, we found that fingerprints were at the origin of a moisture-regulating mechanism.

Soft Miniaturized Actuation and Sensing Units for Dynamic Force Control of Cardiac Ablation Catheters

Soft Miniaturized Actuation and Sensing Units for Dynamic Force Control of Cardiac Ablation Catheters

Prof. Yong-Lae Park

Recently, there has been active research in finding robotized solutions for the treatment of atrial fibrillation (AF) by augmenting catheter systems through the integration of force sensors at the tip.

Permselective metal–organic framework gel membrane enables long-life cycling of rechargeable organic batteries

Permselective metal–organic framework gel membrane enables long-life cycling of rechargeable organic batteries

Prof. Kisuk Kang

Rechargeable organic batteries show great potential as a low-cost, sustainable and mass-producible alternatives to current transition-metal-based cells

Spectroscopic capture of a low-spin Mn(IV)-oxo species in Ni–Mn3O4 nanoparticles during water oxidation catalysis

Spectroscopic capture of a low-spin Mn(IV)-oxo species in Ni–Mn3O4 nanoparticles during water oxidation catalysis

Prof. Ki Tae Nam

High-valent metal-oxo moieties have been implicated as key intermediates preceding various oxidation processes.