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Research Highlights

Research Highlights /

Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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Redirecting electron flows in glutamate oxidases by selective anchoring of osmium complexes

Redirecting electron flows in glutamate oxidases by selective anchoring of osmium complexes

Prof. Taek Dong Chung and Woon Ju Song

L-Glutamate is the most abundant and essential excitatory neurotransmitter in the nervous system. However, its direct electrochemical detection is challenging due to its inherently non-electroactive nature.

Association between antibiotic use and cardiovascular diseases in metabolic dysfunction-associated steatotic liver disease: A nationally representative retrospective cohort study

Association between antibiotic use and cardiovascular diseases in metabolic dysfunction-associated steatotic liver disease: A nationally representative retrospective cohort study

Prof. Sang Min Park

Professor Sang Min Park’s research team from the Department of Biomedical Sciences at SNU examined the association between antibiotic use and cardiovascular disease in metabolic dysfunction-associated steatotic liver disease patients.

A Joint Research Team Led by SNU Professors Ho-Young Kim and Jeong-Yun Sun and GU Professor Keunhwan Park Develops a Liquid Robot Capable of Transforming, Splitting, and Merging Like Living Cell

A Joint Research Team Led by SNU Professors Ho-Young Kim and Jeong-Yun Sun and GU Professor Keunhwan Park Develops a Liquid Robot Capable of Transforming, Splitting, and Merging Like Living Cell

Professors Ho-Young Kim and Jeong-Yun Sun

Seoul National University College of Engineering announced that a joint research team led by Professor Ho-Young Kim from the Department of Mechanical Engineering, Professor Jeong-Yun Sun from the Department of Materials Science and Engineering, and Professor Keunhwan Park from the Department of Mechanical, Smart, and Industrial Engineering at Gachon University has successfully developed a next-generation soft robot based on liquid.

Professor Yousung Jung’s Research Team at SNU Develops Technology to Predict and Interpret the Synthesizability of Novel Materials Using Large Language Models

Professor Yousung Jung’s Research Team at SNU Develops Technology to Predict and Interpret the Synthesizability of Novel Materials Using Large Language Models

Professor Yousung Jung

Seoul National University College of Engineering announced that Professor Yousung Jung’s research team in the Department of Chemical and Biological Engineering has successfully developed a technology that utilizes Large Language Models (LLMs) to predict the synthesizability of novel materials and interpret the basis for such predictions. This study was conducted in collaboration with Fordham University in the United States.

Abrupt sea level rise and Earth’s gradual pole shift reveal permanent hydrological regime changes in the 21<sup>st</sup> century

Abrupt sea level rise and Earth’s gradual pole shift reveal permanent hydrological regime changes in the 21^st century

Prof. Ki-Weon Seo

Rising atmospheric and ocean temperatures have caused substantial changes in terrestrial water circulation and land surface water fluxes, such as precipitation and evapotranspiration, potentially leading to abrupt shifts in terrestrial water storage.

Seoul National University

Association between short-term exposure to air pollution and cardiovascular disease in older adults: A time-stratified case-crossover study in South Korea

Prof. Sang Min Park

Particulate matter (PM) is known to increase the risk of cardiovascular disease (CVD). However, the association between short-term PM exposure and CVD incidence among older adults remains unclear. We aimed to assess the impact of PM2.5 and PMcoarse on CVD risk and its specific types, including overall CVD, coronary heart disease, acute myocardial infarction, ischemic stroke, and hemorrhagic stroke.

Strong cation concentration effect of Ni–N–C electrocatalysts in accelerating acidic CO<sub>2</sub> reduction reaction

Strong cation concentration effect of Ni–N–C electrocatalysts in accelerating acidic CO₂ reduction reaction

Prof. Yun Jeong Hwang

Professor Yun Jeong Hwang's research team from the Department of Chemistry at SNU identified a new strategy to enhance the performance of electrochemical CO2 reduction by applying an acidic electrolyte.

Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration

Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration

Prof. Woo-Jin Kim

Engineering of biomimetic tissue implants with human induced pluripotent stem cells (hiPSCs) holds promise for repairing volumetric tissue loss.

Association of cholecystectomy with short-term and long-term risks of depression and suicide

Association of cholecystectomy with short-term and long-term risks of depression and suicide

Prof. Sang Min Park

Professor Sang Min Park’s research team from the Department of Biomedical Sciences at SNU has successfully conducted a nationwide cohort study using Korea’s National Health Insurance Service database, examining the association between cholecystectomy and mental health outcomes, specifically the risk of depression and suicide.

Astrocytic inhibition of lateral septal neurons promotes diverse stress responses

Astrocytic inhibition of lateral septal neurons promotes diverse stress responses

Prof. Se-Young Choi

Inhibitory neuronal circuits within the lateral septum (LS) play a key role in regulating mood and stress responses. Even though glial cells can modulate these circuits, the impact of astrocytes on LS neural circuits and their functional interactions remains largely unexplored.

Professor Jin Young Kim’s Research Team at SNU Develops an Electrochemical Catalyst for High-Efficiency, Low-Cost, and Eco-Friendly Hydrogen Production

Professor Jin Young Kim’s Research Team at SNU Develops an Electrochemical Catalyst for High-Efficiency, Low-Cost, and Eco-Friendly Hydrogen Production

Prof. Jin Young Kim

Seoul National University’s College of Engineering has announced a major breakthrough in eco-friendly hydrogen production. A research team led by Professor Jin Young Kim from the Department of Materials Science and Engineering,

Seoul National University

Opportunistic AI for enhanced cardiovascular disease risk stratification using abdominal CT scans

Prof. Sang Min Park

This study introduces the Deep Learning-based Cardiovascular Disease Incident (DL-CVDi) score, a novel biomarker derived from routine abdominal CT scans, optimized to predict cardiovascular disease (CVD) risk using deep survival learning.