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Research Highlights

Research Highlights /

Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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SigAlign: an alignment algorithm guided by explicit similarity criteria

SigAlign: an alignment algorithm guided by explicit similarity criteria

Prof. Joohon Sung

Professor Joohon Sung from the Graduate School of Public Health and the Interdisciplinary Program in Bioinformatics at Seoul National University, along with Ph.D. candidate Kunhyung Bahk from the same Bioinformatics program, have presented a new algorithm for genome analysis.

Profiling protein-protein interactions to predict the efficacy of B-cell-lymphoma-2-homology-3 mimetics for acute myeloid leukaemia

Profiling protein-protein interactions to predict the efficacy of B-cell-lymphoma-2-homology-3 mimetics for acute myeloid leukaemia

Prof. Tae-Young Yoon

B-cell-lymphoma-2 (BCL2) homology-3 (BH3) mimetics are inhibitors of protein–protein interactions (PPIs) that saturate anti-apoptotic proteins in the BCL2 family to induce apoptosis in cancer cells.

Partial-convolution-implemented generative adversarial network for global oceanic data assimilation

Partial-convolution-implemented generative adversarial network for global oceanic data assimilation

Prof. Yoo-Geun Ham

The oceanic data assimilation (DA) system, essential for understanding and forecasting global climate variabilities, blends prior information from numerical models with observed data to create the best possible estimates and their uncertainties of oceanic conditions.

Persistent global greening over the last four decades using novel long-term vegetation index data with enhanced temporal consistency

Persistent global greening over the last four decades using novel long-term vegetation index data with enhanced temporal consistency

Prof. Ryu, Youngryel

Advanced Very High-Resolution Radiometer (AVHRR) satellite observations have provided the longest global daily records from 1980s, but the remaining temporal inconsistency in vegetation index datasets has hindered reliable assessment of vegetation greenness trends

Professor Yong-Lae Park's Team at Seoul National University Develops Stretchable Glove for Precise Hand Motion Detection

Professor Yong-Lae Park's Team at Seoul National University Develops Stretchable Glove for Precise Hand Motion Detection

Prof. Yong-Lae Park

A research team led by Professor Yong-Lae Park from the Department of Mechanical Engineering at Seoul National University has developed a stretchable glove capable of accurately estimating finger bone lengths and joint angles.

Microglia gravitate toward amyloid plaques surrounded by externalized phosphatidylserine via TREM2

Microglia gravitate toward amyloid plaques surrounded by externalized phosphatidylserine via TREM2

Prof. Inhee Mook-Jung

Microglia play a critical role as immune cells in the pathological regions of neurodegenerative diseases such as Alzheimer's disease (AD). This study elucidates that TREM2, present on the surface of microglia, recognizes and clears beta-amyloid associated with externalized phosphatidylserine (ePtdSer) during AD progression.

Self-Consistent Many-Body Metrology

Self-Consistent Many-Body Metrology

Prof. Uwe R. Fischer

Professor Uwe R. Fischer's research team from the Department of Physics and Astronomy at SNU has revealed the fundamental importance of incorporating self-consistency in the solution for the many-body evolution of trapped interacting particles, for parameter estimation from measurement data (known as metrology). The impact of self-consistency has been made manifest by evaluating its strong impact on the metrological precision for the parameter estimation in a given measurement protocol.

High-temperature concomitant metal-insulator and spin-reorientation transitions in a compressed nodal-line ferrimagnet Mn<sub>3</sub>Si<sub>2</sub>Te<sub>6</sub>

High-temperature concomitant metal-insulator and spin-reorientation transitions in a compressed nodal-line ferrimagnet Mn₃Si₂Te₆

Prof. Kee Hoon Kim

Symmetry-protected band degeneracy, coupled with a magnetic order, is the key to realizing novel magnetoelectric phenomena in topological magnets.

Constraining the Low-mass End of the Black Hole Mass Function and the Active Fraction of the Intermediate-mass Black Holes

Constraining the Low-mass End of the Black Hole Mass Function and the Active Fraction of the Intermediate-mass Black Holes

Prof. Jong-Hak Woo

It is widely accepted that every massive galaxy hosts a super-massive black hole. However, the origin of these massive black holes are yet to be revealed.

Advancing the Era of Flexible Microelectronics with Micro-LED Integration Technology

Advancing the Era of Flexible Microelectronics with Micro-LED Integration Technology

Prof. Yongtaek Hong

Microdevices can be integrated on conformable substrates to create high-performance and multifunctional human–machine interfaces.

Antibiotic exposure and depression incidence: A cohort study of the Korean population

Antibiotic exposure and depression incidence: A cohort study of the Korean population

Prof. Sang Min Park

Recent research highlights the crucial role of the gut-brain axis in understanding depression etiologies. While burgeoning studies suggest an association between disruptions in gut microbiota and the development of depression, limited longitudinal studies have investigated this link

The Secret to Satiety Unveiled by Seoul National University Researchers!

The Secret to Satiety Unveiled by Seoul National University Researchers!

Prof. Hyung Jin Choi

Professor Hyung Jin Choi's research team from the Department of Brain and Cognitive Sciences at Seoul National University has announced that they have identified the mechanism by which 'glucagon-like peptide-1 (GLP-1)' based obesity treatments reduce body weight for the first time in the world.