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Department of Health Care Convergence October Research Seminar (Monday, Oct. 14, 12:00 PM - 1:00 PM)

Oct 14, 2024

The Department of Health Care Convergence at the Graduate School of Convergence Science and Technology, Seoul National University, is hosting a research seminar as follows:

- Date and Time: Monday, October 14, 2024, 12:00 PM - 1:00 PM

- Speaker: Professor Jeong-Min Kim (Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University)

- Seminar Topic: Super-Resolution Fluorescence Microscopy: Technology Development and Biological Application Research

- Seminar Overview:
Single Molecule Localization Microscopy (SMLM) has transformed optical microscopy by achieving spatial resolutions as fine as 20 nm, enabling new insights into nanoscale structures in cells and their physiological functions. Awarded the 2014 Nobel Prize in Chemistry, this super-resolution technique has extended our understanding of subcellular organization. In this seminar, I will introduce SMLM's foundational principles and our lab's adaptation, oblique plane SMLM (obSTORM), which applies to a broader range of biological samples, including tissues and small animals. I will also present recent efforts to improve obSTORM's imaging performance through the development of a high refractive-index imaging buffer, advanced point spread function modeling, and deep learning-based background fluorescence removal. Additionally, I will briefly cover ongoing biological application studies in our lab using SMLM. SMLM offers new opportunities for nanoscale biological research and advances in medicine.

- Inquiries: Department of Health Care Convergence Administration Office (ddttww0830@snu.ac.kr / 031-787-8169)

We encourage all interested parties to participate.

Thank you.
Department of Health Care Convergence